The GET team developed innovative technologies for high level expression of glycosylated recombinant products in mammalian cells for research and industry. The core product catalog includes an extensive collection of mammalian and bacterial Glyco-Enzymes (glycosyltransferases and glycoside hydrolases) and other recombinant glycoproteins. GET also provides scalable custom glycoprotein production through the use of proprietary expression vectors and mammalian cell lines.
Recombinant products generated by GET employ a proprietary Glo-Enzyme fusion protein strategy that provides efficient production and secretion in mammalian cells. The resulting products retain full enzymatic activity and can be quantified by fluorescence measurement. The technology also allows easy cleavage of fusion tags and remodeling of glycan structures on the recombinant products. The result is a flexible collection of Glyco-Enzymes and glycosylated products that are optimally suited for diverse biochemical, analytical, synthetic, cell biology and biotherapeutic applications.